Merck OSTEOMOLL rapid decalcifier-solution for Histology 1LT
Dekalsifiyerler
Rutin histolojik işlemlerde kemik ve diğer sert dokuların mikroskopik muayenesi için
dekalsifikasyon yöntemleri gereklidir. Dekalsifiye edilecek materyal aşırı dekalsifiyan çözeltinin
içerisine konur ve demineralize (dekalsifiye) edilir. Dekalsifikasyon süresi, sert dokunun boyutuna
ve yapısal yoğunluğuna bağlıdır, dekalsifiyan çözeltisinin bileşimi de işlem üzerinde belirleyici bir etkiye sahiptir.
OSTEOMOLL Dekalsifikasyon Çözümleri
Kemik ve sert dokuların dekalsifikasyonu, mineral tuzlarının asitlerini serbest bırakan ve daha
sonra durulanabilen OSTEOMOLL ’de olduğu gibi inorganik asitlerin kullanımını gerektirir.
Dekalsifiyan çözelti OSTEOMOLL laboratuvardaki diğer berrak sıvılardan (örn. Ksilen ve alkol)
ayırt edilmesini sağlayan mavi bir inert boya içerir. Kullanılan boya, dekalsifiye edilecek doku
üzerindeki herhangi bir etki açısından inerttir.
OSTEOSOFT Dekalsifikasyon Çözümleri
Hassas, kalsiyum içeren doku dekalsifiye edilirken, dokunun kalsiyum iyonlarını bağlayan
kompleks veya şelat oluşturucu maddeler içeren OSTEOSOFT gibi bir çözelti kullanılır. Bu OSTEOMOLL ® - OSTEOSOFT
tip dekalsifiyan çözeltisi, dokudaki antijen yapılarını korur, böylece immünolojik prosedürler
gerçekleştirilebilir. Dekalsifiyan çözelti OSTEOSOFT laboratuvardaki diğer berrak sıvılardan
(yani ksilen ve alkol) ayırt edilmesini sağlayan sarı bir inert boya içerir. Kullanılan boya, dekalsifiye
edilecek doku üzerindeki herhangi bir etki açısından inerttir.

Pricing & Availability

Catalogue Number	Availability	Packaging	Qty/Pack	Price	Quantity
1017361000	— Contact Customer Service	Plastic bottle	1 l	Upon Order Completion More Information	—	Add To Favorites
1017362500	— Contact Customer Service	Plastic bottle	2.5 l	Upon Order Completion More Information	—	Add To Favorites

Description
Catalogue Number	101736
Description	OSTEOMOLL®
Overview	OSTEOMOLL® - Solution for rapid decalcification (with fixation) for histology, is used for human cell diagnostics and serves to decalcify (demineralize) bone tissue (e. g. punched bone-marrow specimens) and other hard materials and to soften keratinized tissue of human origin, fixing the specimens in the same process. Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® (Cat.no. 101728) can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®, can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and hydrochloric acid. The amount of OSTEOMOLL®needed is dependent upon on the size, type and thickness of the material. A 30 ml portion of OSTEOMOLL®, which should completely cover the material, can be used twice if the solution is still clear and not contaminated. The material must first be cut to a thickness of max. 5 mm and an area of 6 cm2 (= max. Embedding cassette size). Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis. Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. The quantity of OSTEOMOLL® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Product Information
HS Code	3822 00 00
Quality Level	MQ400

Applications
Application	Solution for rapid decalcification (with fixation) for histology

Physicochemical Information
Density	1.10 g/cm3 (20 °C)
pH value	<1 (H₂O, 20 °C)

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H290: May be corrosive to metals. H302 + H332: Harmful if swallowed or if inhaled. H314: Causes severe skin burns and eye damage. H317: May cause an allergic skin reaction. H335: May cause respiratory irritation. H341: Suspected of causing genetic defects. H350: May cause cancer.
Precautionary Statement(s)	P201: Obtain special instructions before use. P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal Word	Danger
Storage class	6.1D Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3 highly hazardous to water
Disposal	9 Carcinogenic compounds and flammable compounds labelled "Highly toxic" or "Toxic": container F. Alkyl sulfates are carcinogenic; Take particular care to avoid inhalation and skin contact. To neutralize alkyl sulfates, add dropwise (from a dropping funnel) to concentrated ice-cool Ammonia solution (Cat.No. 105426) with vigorous stirring. Before placing in container D, check the pH with pH Universal indicator strips (Cat.No. 109535).

Safety Information
Categories of danger	harmful, irritant, carcinogenic, sensitizing

Storage and Shipping Information
Storage	Store at +15°C to +25°C.

Transport Information
Declaration (railroad and road) ADR, RID	UN 1789 , 8, II
Declaration (transport by air) IATA-DGR	UN 1789 , 8, II
Declaration (transport by sea) IMDG-Code	UN 1789 , 8, II, Segregation Group: 1 (Acids)

Specifications
Performance test	passes test

Taksit Seçenekleri

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Merck OSTEOMOLL rapid decalcifier-solution for Histology 1 LT

Pricing & Availability

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