Description
Catalogue Number	109272
Description	PAPANICOLAOU'S SOLUTION 3B POLYCHROMATIC
Overview	The cytological staining technique developed by Papanicolaou is still the standard method in cancer and hormone cycle diagnosis. Four different polychrome solutions are available; they differ in the various concentrations of the components and produce different cytoplasm stains. In the last staining step is used the so-called polychrome solution, a mixture of eosin, light green SF and Bismarck brown. The polychrome solution is used to demonstrate the differentiation of squamous cells. In gynecological cytology Polychrome solution EA 31 (3a) and EA 50 (3b) are mostly used. In non-gynecological cytology Polychrome solution EA 65 (3c) and EA 65 (3d) are used. It is an IVD product and CE certified.

Product Information
HS Code	3204 19 00

Physicochemical Information
Density	0.82 g/cm3 (20 °C)
Flash point	17 °C

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H225: Highly flammable liquid and vapour. H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled. H319: Causes serious eye irritation. H370: Causes damage to organs.
Precautionary Statement(s)	P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P240: Ground/bond container and receiving equipment. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311: IF exposed or concerned: Call a POISON CENTER/doctor. P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal Word	Danger
Storage class	3 Flammable Liquids
WGK	WGK 2 water endangering
Disposal	1 Strongly contaminated halogen-free organic solvents: container A.

Safety Information
Hazard Symbols	Toxic Flammable
Categories of danger	highly flammable, toxic
R Phrase	R 11-20/21/22-39/23/24/25 Highly flammable.Harmful by inhalation, in contact with skin and if swallowed.Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
S Phrase	S 16-36/37 Keep away from sources of ignition - No smoking.Wear suitable protective clothing and gloves.

Storage and Shipping Information
Storage	Store at +15°C to +25°C.

Transport Information
Declaration (railroad and road) ADR, RID	UN 1992 , 3 (6.1), II
Declaration (transport by air) IATA-DGR	UN 1992 , 3 (6.1), II
Declaration (transport by sea) IMDG-Code	UN 1992 , 3 (6.1), II

Specifications
Suitability for microscopy (Vaginal smear)	passes test
Nuclei	blue to dark violet
Cyanophilic cytoplasm	blue-green
Eosinophilic cytoplasm	pink

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MERCK 109272 Papanicolaou's solution 3b polychromatic solution EA 50 for cytological cancer and cycle diagnosis

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